Conversely, an increase in Glu levels was also expected, since stress and glucocorticoids, which are very present in BD patients, can increase the concentrations of extracellular Glu in the hippocampi [78] alongside high levels of expression of the GCP II enzyme in the hippocampi of BD patients, which hydrolyzes NAAG into Glu in the glial cells [24]. Here, FOLH1 is linked to Behcet disease.