These results led us to assess the protein levels of PGC-1α in the epididymis, and we observed that the rats in the T2DM group showed lower levels of PGC-1α (0.68 ± 0.22-fold variation to control) (by 32%) in relation those of the control group (1.00 ± 0.09-fold variation) (SP = 96%) (Figure 2). The gene discussed is PPARGC1A; the disease is type 2 diabetes mellitus.