No changes were noted for the genes: CDKN2A (P16INK4A, Cyclin-dependent kinase inhibitor 2A, melanoma, p16, inhibits CDK4), IL1B (Interleukin 1, beta), KRAS (V-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog), MTSS1 (Metastasis suppressor 1), NF2 (Neurofibromin 2, merlin), NME1 (NM23, Non-metastatic cells 1, protein), PTEN (Phosphatase and tensin homolog), RB1 (Retinoblastoma 1), TGFB1 (Transforming growth factor, beta 1) and MYC (V-myc myelocytomatosis viral oncogene homolog (avian)). The gene discussed is IL1B; the disease is melanoma.