IL6 and Chronic colitis: Co-culture with T-MSC clearly inhibited the PMA-stimulated proliferation of splenocytes by 60%; TMSC [×4] treated mice’s survival rate was improved to that of the normal. TMSC [×2] injection also significantly improved the survival rate to 89% of the control. TMSC [×4] treatment inhibits DSS-induced colon shortening; TMSC injection does no inhibit histopathological alterations in the distal colon in the chronic colitis mouse model, although it ameliorates IL-1Beta and IL-6 mRNA production in chronic colitis mice.