MAP2K7 and gastric cancer: Complementary to these findings, BA exerted its antiproliferative effect in another drug-resistant gastric cancer cell line, SGC-7901, through the induction of autophagy as confirmed by the formation of autophagosomes and the down-regulation of ERK/MEK signaling pathway, and further confirmed by decreased levels of phosphorylated ERK and MEK proteins (Figure 4; Table 1) [27].