Since we found a significant induction of IFITM3 in response to various inflammatory stressors (LPS, TNFα, and IFNγ) and recent findings suggest a novel role of IFITM3 in amyloid pathology, we sought to examine whether amyloid peptide could induce IFITM3 expression in primary microglia. The gene discussed is IFNG; the disease is amyloidosis.