The Genehancer database was also searched, corroborating that the same five ACBD3 variants were associated with core binding factor acute myeloid leukaemia risk; additionally, ACBD3 regulatory region variants were found that enhanced the red blood cell distribution width (a measure of red blood cell volume variation), and variants that are associated with plateletcrit (the percentage of blood volume occupied by platelets) [43]. This evidence concerns the gene ACBD3 and acute myeloid leukemia.