ACBD3 staining was significantly higher in PR- breast cancer cores compared to PR 3+ cores on one array and significantly higher in HER2− cores compared to HER2 1+ cores on another array, but this result could not be cross-correlated between slides because only one slide had PR 3+ breast cancer patients and that same slide held no HER2 1+ patients. This evidence concerns the gene ERBB2 and breast cancer.