URI and TRI shared differences in pathways compared to MIC including Tyrobp casual network in microglia, type II interferon signaling, spinal cord injury, peptide GPCRs, microglia pathogen phagocytosis pathway, matrix metalloproteinase, macrophage markers, lung fibrosis, IL-5-signaling pathway, G1 to S cell cycle control, DNA replication, cytokines and inflammatory response, circulating monocytes and cardiac macrophage in diastolic dysfunction, chemokine signaling pathway and apoptosis. Here, IL5 is linked to pulmonary fibrosis.