Overall, those studies shows that CXCL1, CXCL2, CXCL5, CXCL6, CXCL7, CXCL9, CXCL10, CXCL12, CXCL14, CXCL16 and CXCL17 may be novel prognostic markers of HCC. The gene discussed is CXCL12; the disease is hepatocellular carcinoma.