Potential marker metaproteins for NASH and HCC were a decreased abundance of the sn-glycerol-3-phosphate import ATP-binding protein (#SpecAb_C: 0.55%%, #SpecAb_NASH: 0.20%, #SpecAb_HCC: 0.25%; unknown superkingdom) and ketol-acid reductoisomerase (NADP(+)) (#SpecAb_C: 0.51%, #SpecAb_NASH: 0.20%, #SpecAb_HCC: 0.27%), and increased abundances for the kielin/chordin-like protein (#SpecAb_C: 0.84%, #SpecAb_NASH: 2.96%, #SpecAb_HCC: 3.28%; class: Mammalia) and protein S100-A9 (#SpecAb_C: 0.09%, #SpecAb_NASH: 0.34%, #SpecAb_HCC: 0.39%; unknown superkingdom). Here, KCP is linked to metabolic dysfunction-associated steatohepatitis.