Compared with other diseases, ESKD has a higher mortality rate and involves a greater utilization of outpatient, emergency, and inpatient services due to its more complex clinical comorbidities (e.g., diabetes, heart diseases, anemia, cardiovascular diseases (stroke and peripheral vascular disease), lower albumin levels, and lower hematocrits) and higher risks of stroke, myocardial infarction, congestive heart failure, infectious disease, and sepsis [3,9,10]. The gene discussed is ALB; the disease is stroke disorder.