Recent evidence suggests that genetic defects in the ACTC1 gene are associated with IDC (idiopathic dilated cardiomyopathy), FHC (familial hypertrophic cardiomyopathy), and ASD and that additional mutations in ACTC1 gene might implicated in such type of cardiomyopathy [23]. The gene discussed is ACTC1; the disease is hypercholesterolemia, familial, 1.