Recently, urinary proteomic profiling performed by Araumi revealed that the combination of uRBP4 and urinary SH3 domain-binding glutamic acid-rich-like protein 3 (uSH3BGRL3) could clearly distinguish between MCD with nephrotic syndrome and diabetic kidney disease (DKD) (AUC = 0.974). Here, SH3BGRL3 is linked to nephrotic syndrome.