SPTLC3 and metabolic syndrome: A total of 10 SNPs (rs75397325, rs4246316, rs80165332, rs62106618, rs12358192, rs11006229, rs10826014, rs149162405, rs6109681, and rs3906631) found in six genes (CERS3, CERS6, ACER1, SGMS1, SPTLC2, and SPTLC3) showed associations with elevated plasma levels of at least one of the ceramide types in MetS group (FDR-adjusted p values <5.0 × 10−2) (Table 3).