AFP and hepatocellular carcinoma: Univariate analysis of prognostic factors for progression-free survival in patients with HCC demonstrated high hsa_circ_0003570 expression (hazard ratio [HR], 0.580; 95% CI, 0.388–0.867; p = 0.008); multiple tumors (HR, 1.950; 95% CI, 1.316–2.889; p = 0.001); AFP level >200 ng/mL (HR, 2.767; 95% CI, 1.845–4.148; p < 0.001); poor CTP class (HR, 2.869; 95% CI, 1.676–4.911; p < 0.001); and curative treatment (HR, 0.186; 95% CI, 0.120–0.288; p < 0.001).