Similar to our results, it was previously shown that LHX2 silencing weakened the migration and invasion of non-small cell lung cancer (NSCLC) [25], and LHX2 overexpression promoted cell proliferation by activating β-catenin/TCF signaling in pancreatic ductal adenocarcinoma [12]. The gene discussed is HNF4A; the disease is pancreatic ductal adenocarcinoma.