While in the current study, selectivity for KRAS G4mid over G4near and MYC was observed, only a small subset of target G4s were examined and the cytotoxicity across pancreatic cancer cell lines is most likely related to promiscuity of G4 binding and stabilization for compound 9a, as frequently noted with G4-interactive compounds. The gene discussed is KRAS; the disease is familial pancreatic carcinoma.