VPS35 and Parkinson disease: Although the exact mechanisms underlying PD remain a mystery, recent clinical research has revealed that a number of proteins, such as PTEN (phosphatase and tensin homolog)-prompted putative kinase 1 (PINK1), α-synuclein (SNCA), VPS35, glucocerebrosidase (GBA), Parkin (PRKN), DJ-1, and leucine-rich repeat kinase 2 (LRRK2), are linked to the progression of PD [12,13].