Familial hypercholesterolemia (FH) is an inherited, autosomal dominant metabolic disorder mostly caused by disease-causing variant in LDLR (low-density lipoprotein receptor gene), APOB (apolipoprotein B gene) or PCSK9 (proprotein convertase subtilisin/kexin type 9 gene). This evidence concerns the gene PCSK9 and familial hyperaldosteronism.