Another pilot study recently confirmed the potential of HA-based moisturizers for the treatment of GSM in cancer survivors: 101 women either with a history of hormone receptor-positive (HR+) BC undergoing adjuvant therapy with an AI, or with HR+ endometrial cancer treated with surgery and postoperative radiotherapy, used an HA-based vaginal gel to relieve GSM-associated symptoms for up to 24 weeks. The gene discussed is NR4A1; the disease is cancer.