TGFB1 and cancer: Through an extensive immunogenomic analysis of pan-cancer, six immune subtypes, including wound healing (C1), IFN-γ dominant (C2), inflammatory (C3), lymphocyte depleted (C4), immunologically quiet (C5) and TGF-β dominant (C6), were identified according to differences in immune, genetic and clinical features, in which C3 had great OS, C2 and C1 had poor prognosis, while C4 and C6 had the least favorable outcomes [32].