Hereditary paraganglioma-pheochromocytoma syndrome (PGL/PCC) involves pathogenic variants of the succinate dehydrogenase (SDH) gene and is associated with the development of paragangliomas, pheochromocytomas, gastrointestinal stromal tumors, and RCC [37]. This evidence concerns the gene SDHB and hereditary pheochromocytoma-paraganglioma.