Due to its overexpression on the surface of prostate cancer cells and its extracellular binding pocket for small-molecule ligands, glutamate carboxypeptidase II (GPII), also known as prostate-specific membrane antigen (PSMA), is a relatively novel effective target for molecular imaging and radioligand therapy (RLT) in prostate cancer [1]. The gene discussed is FOLH1; the disease is prostate carcinoma.