In addition to these types of cells, after a comprehensive understanding of exosomes, the administration of mast cells stimulated by hepatitis C virus E2 envelope glycoprotein or exosomal shuttle microRNAs from those cells can inhibit the metastasis of HCC cells, which may ultimately lead to the longer survival of HCC patients [114]. The gene discussed is ERVW-1; the disease is hepatocellular carcinoma.