CCR6 and neoplasm: Similarly, in ID8-Vegf Defb29 (ID8 cells producing high amounts of VEGF-A and beta-defensins) tumors and ascites, MHC-II+CD11c+DEC205+CD8a+ DCs with low expression of co-stimulatory molecules were found to be increasingly attracted to the tumor via CCR6 and enhanced tumor growth by achieving endothelial cell-like features and aiding in tumor vasculogenesis [85].