To investigate the similarity and discrepancy of m6A regulator expression patterns between PCas, we first performed consensus clustering on 495 PCa samples from the TCGA PRAD dataset using 21 pre-defined m6A regulators (METTL3, METTL14, RBM15, RBM15B, WTAP, KIAA1429, CBLL1, ZC3H13, ALKBH5, FTO, YTHDC1, YTHDC2, YTHDF1, YTHDF2, YTHDF3, IGF2BP1, HNRNPA2B1, HNRNPC, FMR1, LRPPRC, ELAVL1). This evidence concerns the gene ALKBH5 and posterior cortical atrophy.