Regarding CNAs, the main affected genes in this series of primary MN that recurred are located on chromosomes 22q (TIMP3), 1p (TP73), 6q (ESR1 and PARK2), and 18q (BCL2); the association among these chromosomes’ alterations and tumor recurrence has been previously demonstrated [1,4,29]. Here, ESR1 is linked to neoplasm.