Leucine-rich repeat containing 15 (LRRC15) has been reported to be expressed in the CAFs of many solid tumors, including pancreatic cancer, and in a subset of mesenchymal cancer cells [75], and scRNA-seq of PDAC mouse models revealed that LRRC15 is expressed in TGF-β-driven CAFs that may correspond to myCAFs [39]. Here, LRRC15 is linked to pancreatic neoplasm.