ETV6 and acute lymphoblastic leukemia: Variant allele rs1573613 T>C of ETV6 seems to weaken the binding of miR-34c-5p and miR-449b-5p (resulting in 17% and 33% increase protein levels relative to the T allele, respectively), whereas these interactions double the risk for childhood ALL (OR, 1.9; 95% CI: 1.16 to 3.11; p < 0.05) [206].