CD34 and acute lymphoblastic leukemia: Accordingly, a qRT-PCR study on adults with ALL reported significantly lower levels of oncomiR miR-92a in fresh leukemia cells compared with CD34+ cells obtained from healthy volunteers (p = 0.0014), significantly lower expression of miR-92a in ALL subjects compared to controls (p = 0.001) and a significantly higher cell-to-plasma ratio of miR-92a in ALL cells (p < 0.0001) compared with those in peripheral blood specimens obtained from healthy individuals, indicating that leukemia cells retain miR-92a [204].