This miRNA, together with miR-7 and miR-195,s seem to play a crucial role in pediatric T-ALL, invariably downregulated in most T-ALL subgroups: TLX1-, TLX3- and TAL1-deregulated, PICALM-MLLT10 and inv(7) cases [79]. This evidence concerns the gene TLX3 and acute lymphoblastic leukemia.