In addition, children with T-ALL/CD56+ seem to have significantly higher miR-221 levels compared with T-ALL/CD56- patients (271.4-fold; CD56 or NCAM1 i.e., neural cell adhesion molecule 1 expression confers poor prognosis in T-ALL), and pediatric immature T-ALL cases have significantly higher miR-221 levels than all other T-ALL subgroups [20,73]. The gene discussed is NCAM1; the disease is acute lymphoblastic leukemia.