Our novel findings in PC are consistent with dependency on high levels of MDM4 in triple-negative breast cancers (TNBCs) expressing mutant p53 (e.g., [25,59] and further with accelerated tumourigenesis in mouse mammary gland tumours with mutant p53 model that overexpressed MDM4 [60]). The gene discussed is MDM4; the disease is triple-negative breast carcinoma.