IL6 and neoplasm: In other tumor entities, including lymphomas [115], lung [215], and gastric cancer [231,232], IL6, IL8, IL17, IL23, and TNFα secreted by monocytes, macrophages, neutrophils, and non-MSC stromal cells were shown to be capable of promoting malignant transition of ASCs/MSCs, which was associated with significantly increased metastatic rates and tumor growth [115,215,227,231,232].