The supernatant of ASCs, which were isolated from breast cancer tissue, was reported to upregulate a panel of anti-inflammatory cytokines, such as IL4, IL10, CCR4, CD25, and TGFβ in peripheral blood lymphocytes (PBLs) and to increase the number of Tregs, which could establish an anti-inflammatory reaction in the TME [110]. The gene discussed is TGFB1; the disease is breast cancer.