All aberrations found in this cohort were previously described in childhood BCP-ALL, where KMT2A rearrangements are seen in ~6% of the patients, a hyperdiploid karyotype and ETV6-RUNX1 fusions in ~20–25% of the patients and iAMP21 in ~2% of the patients [18]. This evidence concerns the gene KMT2A and acute lymphoblastic leukemia.