Golan-Gerstl et al. reported that the splicing factor heterogeneous nuclear ribonucleoprotein (hnRNP) A2/B1, which is overexpressed in GBM, regulates AS events of the proto-oncogenes RON, BIN1, c-FLIP, and WWOXp to promote malignant transformation and is associated with poor patient prognosis [91]. The gene discussed is CFLAR; the disease is glioblastoma.