With the drastically expanding knowledge of BC intracellular and extracellular profiles offered by large-scale omics datasets, more putative, predictive biomarkers, such as PIK3CA and p53 genomic mutations, overexpression of E-cadherin and catenins, tissue inhibitors of metalloproteinases, prostate-specific antigen, tissue factor, and urokinase plasminogen activator (uPA) protein abundance, have been highlighted either in the context of patient survival or response to chemotherapy [13,14,15,16,17,18,19,20,21,22,23]. Here, PLAU is linked to breast cancer.