As such, from the above-mentioned biomarkers, while all have been extensively associated with cancer states, only HSPG2 [96], ACTG1 [101,102], and LAMA5 [107] are not significantly elevated in other non-cancerous conditions, e.g., infection, auto-immunity, and ischemia (Figure S2, Table S5). Here, HSPG2 is linked to cancer.