We also identified biomarkers, namely, ITGB1, FBN1, and THBS1, secreted by BC cells constituting lesions of all grades as well as the examined adenocarcinomas (colorectal, gastric, hepatocellular, melanoma, non-small cell lung cancer, ovarian, pancreatic, and prostate cancer). The gene discussed is THBS1; the disease is Familial prostate cancer.