IL-6, the best-known protumor cytokine, and its family of cytokines, including IL-11, IL-27, IL-31, cardiotrophin-1, ciliary neurotrophic factor, leukemia inhibitory factor (LIF), and oncostatin M (OSM), are involved in crucial physiological and/or pathological processes, such as cell growth, survival, differentiation, energy metabolism, angiogenesis, migration, invasion, metastasis, inflammation, and autoimmune diseases [6,7,8,9,10]. This evidence concerns the gene IL6 and autoimmune disease.