NFKB1 and colorectal cancer: Doxorubicin treatment has been shown to enhance MMP9 expression in H9c2 rat heart-derived embryonic myocytes [21], an effect that was reported to be mediated by p38 kinase, whereas NF-κB has been reported to promote MMP9 expression and 5′-fluorouracil resistance in colorectal cancer cell lines [22].