In the following study [111], neutrophil activation markers activin A (a cytosolic neutrophil protein), interleukin 8 (IL-8) (a chemoattractant for neutrophils) and MPO (a neutrophil biomarker released in tissues) were determined in plasma and urine in critically ill sepsis patients with AKI. This evidence concerns the gene CXCL8 and acute kidney injury.