There are four members within this family of receptors, the Ovarian Cancer G-Protein Coupled Receptor Protein1 (OGR1, GPR68), G-protein Coupled Receptor 4 (GPR4), G2 accumulation (G2A, GPR132), and T Cell Death-Associated Gene 8 (TDAG8, GPR65) [27,28,29,30]. The gene discussed is GPR65; the disease is ovarian carcinoma.