Thus, we suggest an in-depth study on the improvement effect of Rg1 on neurological diseases among these three miRNAs (miR-134, miR-144, and miR-873-5p) or other miRNAs—whether Rg1 could affect the regulation of different target genes by the same miRNA in neurological diseases, and whether Rg1 can affect the regulation of the same target gene by different miRNAs. This evidence concerns the gene PPP1R3A and nervous system disorder.