EZH2 and glioblastoma: These encompass histone deacetylase (HDAC) inhibitors (e.g., vorinostat) [237], enhancer of zeste homolog 2 (EZH2) inhibitors (which now include FDA-approved drug tazemetostat) [238], a thalidomide derivative lenalidomide [239], and antibiotic quinomycin A [240], most of which have been shown to have an antitumor effect on GBM cell lines in vitro or in vivo [241,242,243].