Apart from the aforementioned markers of LSEC function/dysfunction, the expression of FABP4, fatty acid-binding protein 5 (FAPB5), von Willebrand factor (VWF), von Willebrand factor A domain-containing 1 (VWA1), and CD31 was found to be upregulated in LSECs during liver disease [49,142,148]. The gene discussed is VWA1; the disease is liver disorder.