CDH2 and hepatocellular carcinoma: Therefore, to investigate whether E- and N-cadherin were detected in one complex in liver and HCC tissue in situ, we performed confocal laser scanning fluorescence microscopy of normal liver tissue, and both E- and N-cadherin were colocalized with the plaque proteins α- and β-catenin at the AJs at the border to the bile canaliculi and at the basolateral cell membrane (Figure 3).