TWIST1 and hepatocellular carcinoma: In the original publication by Fang et al., fewer cases with reduced E-cadherin expression were found in the VETC-positive HCC compared to the VETC-negative HCC, while N-cadherin was not investigated [76]; however, given the minimal differences, the link between the VETC pattern and E-cadherin expression may be explained by the significantly higher statistical power in our larger cohort—Fang’s group did not only analyze E-cadherin, but also other factors of EMT, such as Snail, Slug, and Twist, which may validate the notion that there is no relationship between VETC and EMT.