In line with this, we have previously shown the presence of E- and N-cadherin in cholangiocytes of the biliary tree and derived tumors, suggesting N-cadherin as a marker to distinguish between intrahepatic cholangiocarcinoma and liver metastases of ductal adenocarcinoma of the pancreas [89]. The gene discussed is CDH2; the disease is pancreatic ductal adenocarcinoma.