CDH2 and hepatocellular carcinoma: To investigate whether E- and N-cadherin heterodimer-containing AJ are also retained in hepatocellular tumors and derived cell cultures, we performed immunoprecipitation experiments with antibodies against E- and N-cadherin and an unrelated antibody of the same species (mouse myeloma antibody) in whole-cell lysates of PLC cells, as well as in lysates of human normal liver and human HCC tissue.