The activation of apoptosis following RB administration, even with different dosage schemes, was similarly reported in neuroblastoma cells [63], in melanoma following UV-A and B exposures [64], in ovarian and in breast cancer cells [22,65], while, to date, no studies have been documented on RB effects in human astrocytoma cells. Here, RB1 is linked to astrocytoma (excluding glioblastoma).