HSPG2 and myocardial disorder: We have extensively reviewed the literature regarding the involvement of phospholipid-mediated signal transduction mechanisms in different myocardial diseases [101,102,103,104,105,106], and recently the involvement of PLC in the cardiomyocyte hypertrophic response to norepinephrine [107] as well as the role of PLC in the catecholamine-induced increase in cardiomyocyte protein synthesis [108] has also been reviewed.