IGF1 and bone disorder: The cutoff values of IGF-1 for predicting these bone disorders were 61.5 ng/mL (area under the curve: 0.74; sensitivity/specificity: 0.545/0.894), 69.5 ng/mL (0.70; 0.633/0.784) and 61.5 ng/mL (0.74; 0.512/0.929), respectively (Figure 5A,B).