The result of this study is consistent with previous studies that levels of serum ALT and AST are not a good candidate as a biochemical marker for the diagnosis and grading of US-detectable subclinical hepatic fibrosis among schistosomiasis patients in the absence of other diseases affecting the liver such as viral hepatitis, alcoholic liver disease, and non-alcoholic fatty liver disease [7,11,27,28]. Here, GPT is linked to viral hepatitis.