Bazick et al. collected data from a large cohort derived from the NASH Clinical Research Network studies and demonstrated that advanced age, higher AST/ALT and waist-to-hip ratios, hypertension, isolated abnormal alkaline phosphatase, hematocrit, serum insulin, and low platelet counts are associated with advanced liver fibrosis [32]. The gene discussed is GPT; the disease is Hepatic fibrosis.