Regarding pneumonia in the adult population, in the study by Cavalli R. et al. [88] from 2014, MR-proADM levels were correlated with mortality; Pereira J.M. et al. [89], remarked that patients with severe CAP who have decreased levels of MR-proADM after 48 h of antibiotic treatment have a better vital prognosis, as well as the study by Akpinar S. et al. [90], who observed that the determination of MR-proADM alone does not correlate with mortality or disease severity to produce mortality but that the union of SOFA, APACHE II and MR- proADM may be good prognostic markers in CAP patients. The gene discussed is BTBD8; the disease is pneumonia.