PPP3CA and juvenile polyposis syndrome: Supplementary Table S2 shows the virulence genes of all strains causing PJI according to clinical evolution. All isolates harbored genes encoding microbial surface components recognizing adhesive matrix molecules (MSCRAMMs) and genes involved in biofilm formation. The genes fnbpA and fnbpB were identified in 100 and 85.7% of isolates, respectively, while cna was present in only 64.3%.