ALK and cancer: A number of drugs containing the pyrazole ring have been clinically tested and reported in the literature, including Lonazolac (a), a non-steroidal anti-inflammatory drug (NSAID); Diphenamizole (b), an NSAID and analgesic; Crizotinib (c), an anti-cancer drug acting as an inhibitor of ALK (anaplastic lymphoma kinase) and ROS; Pyrazomycin (d), an antibiotic, antineoplastic and antiviral drug (Figure 1) [7].